Isoproterenol; Hydrochloride 1PC X 100MG

Code: 420355-100MG D2-231

Biochem/physiol Actions

Cell permeable: no

Reversible: no

Product does not compete with ATP.

Primary Targetβ-adrenergic agonist

General d...


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Your Price
€74.40 100MG
€91.51 inc. VAT

Biochem/physiol Actions

Cell permeable: no

Reversible: no

Product does not compete with ATP.

Primary Targetβ-adrenergic agonist

General description

Phenethylamine derivative. Selective β-adrenergic agonist that increases cytosolic cAMP. Promotes glycogen breakdown and causes bronchodilation. Increases Cl- diffusion and potential difference in rabbit trachea cells through nitric oxide generation.

Phenethylamine derivative. Selective β-adrenergic agonist that stimulates adenylate cyclase activity. Promotes glycogen breakdown and causes bronchodilation. Increases Cl diffusion and potential difference in rabbit trachea cells through nitric oxide generation. Reported to activate MAP Kinase (ERK) by a Rap1 and B-Raf dependent process.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Schmitt, J.M., and Stork, P.J. 2000. J. Biol. Chem.275, 25342.Carmena, M.J., et al. 1997. Prostate 33, 46.Takemura, H., et al. 1995. J. Pharmacol. Exp. Ther. 274, 584.Kishimoto, I., et al. 1994. J. Biol. Chem.269, 28300.Macaulay, S.L., et al. 1994. Mol. Cell Biochem.141, 27.Yashiro, K., et al. 1994. J. Biochem.115, 1040.Ladenheim, R.G., et al. 1993. J. Neurochem.60, 260.von Zastrow, M., et al. 1993. J. Biol. Chem.268, 763.Mokhtari, A., et al. 1985. J. Cyclic Nucleotide Protein Phosphorylation Res.10, 213.

Packaging

100 mg in Plastic ampoule

Reconstitution

Unstable in solution; reconstitute just prior to use.

Warning

Toxicity: Irritant (B)

assay≥99% (TLC)
colorwhite, white to off-white
formsolid
InChI keyIROWCYIEJAOFOW-UHFFFAOYSA-N
InChI1S/C11H17NO3.ClH/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;/h3-5,7,11-15H,6H2,1-2H3;1H
manufacturer/tradenameCalbiochem®
Quality Level100
shipped inambient
solubilitywater: soluble, ethanol: soluble
storage conditionprotect from light, OK to freeze
storage temp.10-30°C
Cas Number51-30-9
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